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5-[Bis(Cyclohexyl)Phosphino]-1',3',5'-Triphenyl-1,4'-Bi-1H-Pyrazole CAS NO 1021176-69-1


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CAS No.:1021176-69-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-[Bis(Cyclohexyl)Phosphino]-1',3',5'-Triphenyl-1,4'-Bi-1H-Pyrazole is a specialized organophosphorus ligand designed for advanced catalytic applications. This compound matters for its ability to facilitate highly selective and efficient cross-coupling reactions, which are critical in the synthesis of complex organic molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and high-performance polymers.

Application

  • As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig amination.
  • For the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring high stereoselectivity.
  • In the development of agrochemicals, including novel herbicides and fungicides.
  • For academic and industrial research in organometallic chemistry and catalysis.
  • In the preparation of fine chemicals and specialty materials where precise molecular control is essential.
  • As a key component in catalyst systems for C-H activation and C-X bond formation.

Basic Information

Product Name 5-[Bis(Cyclohexyl)Phosphino]-1',3',5'-Triphenyl-1,4'-Bi-1H-Pyrazole
CAS No. 1021176-69-1
Molecular Formula C36H41N4P
Molecular Weight 560.71 g/mol
Synonyms 5-[Bis(cyclohexyl)phosphino]-1',3',5'-triphenyl-1,4'-bipyrazole; 5-(Dicyclohexylphosphino)-1',3',5'-triphenyl-1,4'-bipyrazole; BippyPhos; BippyPhos Ligand; 1021176-69-1; 5-(Dicyclohexylphosphanyl)-1',3',5'-triphenyl-1,4'-bipyrazole
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Quality Control

Our 5-[Bis(Cyclohexyl)Phosphino]-1',3',5'-Triphenyl-1,4'-Bi-1H-Pyrazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing the specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, minimize exposure to air and moisture during handling.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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