Description

Sumatriptan-D6 CAS NO 1020764-38-8 is a deuterium-labeled analog of Sumatriptan, a selective serotonin receptor agonist. This stable isotope-labeled compound is an essential reference standard and internal standard in quantitative bioanalytical research. It is primarily used by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities for method development and validation in pharmacokinetic and metabolism studies. The high isotopic purity and chemical stability ensure reliable and accurate mass spectrometry results.

Application

• Used as an internal standard for the accurate quantification of Sumatriptan in biological matrices (e.g., plasma, serum) via LC-MS/MS and GC-MS.
• Serves as a critical reference material in the development and validation of bioanalytical methods for clinical and preclinical studies.
• Essential for conducting drug metabolism and pharmacokinetics (DMPK) research, including absorption, distribution, metabolism, and excretion (ADME) studies.
• Applied in pharmaceutical quality control and impurity profiling to ensure drug substance and product purity.
• Facilitates forensic and toxicological analysis for the detection and confirmation of Sumatriptan.
• Supports academic and institutional research investigating the pharmacological mechanisms of serotonin receptor agonists.

Basic Information

Item	Detail
Product Name	Sumatriptan-D6
CAS No.	1020764-38-8
Molecular Formula	C14H15D6N3O2S
Molecular Weight	301.43 g/mol
Synonyms	Sumatriptan-d6; 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide-d6; 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide-d6; GR 43175-d6; Imigran-d6; Deuterated Sumatriptan; [2H6]-Sumatriptan
EINECS	Contact for details

Quality Control

Every batch of Sumatriptan-D6 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as isotopic purity, chemical purity (by HPLC), and residual solvent content. Our quality commitment aligns with the needs of GMP/GLP-compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98.0 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.