Description

2-Amino-3-[(Methyl-D3)Amino]-5-Phenylpyridine is a deuterated pyridine derivative of significant interest in advanced chemical research and development. This compound is valued for its role as a key intermediate or analytical standard in the synthesis of isotopically labeled molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, metabolism studies, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• As a deuterated building block in the synthesis of isotopically labeled pharmaceutical compounds for drug discovery and development.
• Use as an internal standard in analytical methods such as LC-MS and NMR for accurate quantification and metabolic studies.
• Intermediate in the research of kinase inhibitors and other targeted therapies where the pyridine scaffold is prevalent.
• Application in mechanistic studies and reaction pathway elucidation using deuterium labeling techniques.
• Key material in the development of Positron Emission Tomography (PET) tracers and other diagnostic agents.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry programs.

Basic Information

Product Name	2-Amino-3-[(Methyl-D3)Amino]-5-Phenylpyridine
CAS No.	1020719-03-2
Molecular Formula	C12H12D3N3
Molecular Weight	202.27 g/mol
Synonyms	2-Amino-3-[(Methyl-d3)amino]-5-phenylpyridine; 5-Phenyl-3-[(methyl-d3)amino]pyridin-2-amine; 2-Amino-3-(methylamino-d3)-5-phenylpyridine; Deuterated 2-Amino-3-(methylamino)-5-phenylpyridine; (Methyl-d3)-labeled 2,3-Diamino-5-phenylpyridine; 1020719-03-2; 2-Amino-3-(N-methyl-d3-amino)-5-phenylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-[(Methyl-D3)Amino]-5-Phenylpyridine is produced under controlled conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to confirm identity, chemical purity, and deuterium incorporation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistent quality and traceability for your research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.