Description

1-Phenyl-5-Trifluoromethyl-Pyrrolidin-2-One is a high-value, fluorinated pyrrolidinone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of the pyrrolidinone scaffold and the trifluoromethyl group, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the trifluoromethyl group enhances bioavailability and stability.
• Material Science Precursor: Serves as a monomer or functional additive in the creation of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated analogs.
• Ligand and Catalyst Development: The structural motif can be utilized to develop novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-Phenyl-5-Trifluoromethyl-Pyrrolidin-2-One
CAS No.	1020717-92-3
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	5-(Trifluoromethyl)-1-phenylpyrrolidin-2-one; 1-Phenyl-5-(trifluoromethyl)-2-pyrrolidinone; 5-Trifluoromethyl-1-phenyl-2-pyrrolidone; α-Phenyl-α'-(trifluoromethyl)succinimide (reduced form); N-Phenyl-5-trifluoromethyl-2-pyrrolidone; 1020717-92-3; 1-Phenyl-5-trifluoromethylpyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our 1-Phenyl-5-Trifluoromethyl-Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.