Description

12,12'-Bis(Diphenylphosphino)-9,9',10,10'-Tetrahydro-11,11'-Bi-9,10-Ethenoanthracene, Min. 98% Catphos is a high-purity, sterically demanding bidentate phosphine ligand designed for advanced catalytic applications. Its unique rigid backbone structure provides exceptional control over metal coordination geometry, which is critical for achieving high selectivity and activity in asymmetric synthesis. This ligand is an essential tool for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel catalytic processes.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Cross-Coupling Catalysis: Employed in Buchwald-Hartwig amination, Suzuki-Miyaura, and other C-C/C-N bond-forming reactions requiring robust, electron-rich phosphine ligands.
• Homogeneous Catalyst Development: Serves as a privileged scaffold for constructing novel transition metal complexes (Rh, Pd, Ru, Ir) with tailored reactivity and stability.
• Pharmaceutical Intermediate Synthesis: Enables the production of high-value, single-enantiomer compounds for drug discovery and development pipelines.
• Agrochemical Research: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Material Science: Potential application in the synthesis of specialized polymers and organic electronic materials via metal-mediated polymerization.

Basic Information

Product Name	12,12'-Bis(Diphenylphosphino)-9,9',10,10'-Tetrahydro-11,11'-Bi-9,10-Ethenoanthracene, Min. 98% Catphos
CAS No.	1020670-88-5
Molecular Formula	C52H40P2
Molecular Weight	726.82 g/mol
Synonyms	Catphos; 9,9',10,10'-Tetrahydro-11,11'-bi-9,10-ethenoanthracene-12,12'-diylbis(diphenylphosphine); 12,12'-Bis(diphenylphosphino)-9,9',10,10'-tetrahydro-11,11'-bi-9,10-[1,2]benzenoanthracene; DTBP-ANTHRO; DTBP-Anthracene; Bidentate Anthracene-Based Phosphine Ligand; (Ra,Sa)-DTBPA
EINECS	Contact for details

Quality Control

Every batch of Catphos is manufactured and tested under strict quality management protocols to ensure consistent high purity and performance. Our standard minimum 98% purity is verified by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 98.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.