Description

4-(3-Fluorophenyl)Pyrrolidin-2-One CAS NO 1019650-87-3 is a high-purity fluorinated pyrrolidinone derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a fluorinated aromatic ring with a lactam moiety, making it a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, particularly in fluorination chemistry and heterocycle formation.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) producing custom intermediates for client projects.

Basic Information

Product Name	4-(3-Fluorophenyl)Pyrrolidin-2-One
CAS No.	1019650-87-3
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	4-(3-Fluorophenyl)-2-pyrrolidinone; 4-(3-Fluorophenyl)pyrrolidin-2-one; 2-Pyrrolidinone, 4-(3-fluorophenyl)-; 3-Fluoro-4-pyrrolidin-2-one benzene; 1019650-87-3; 4-(3-Fluorophenyl)-2-pyrrolidone; 4-(m-Fluorophenyl)-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.