Description

1-Bromo-4-[(3-Fluorophenyl)Methoxy]Benzene is a high-purity, specialty aromatic ether building block designed for advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both bromine and fluorine substituents, making it a versatile intermediate for constructing complex molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for applications such as drug discovery, material science, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl systems.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Bromo-4-[(3-Fluorophenyl)Methoxy]Benzene
CAS No.	1019123-14-8
Molecular Formula	C13H10BrFO
Molecular Weight	281.12 g/mol
Synonyms	4-Bromo-1-[(3-fluorophenyl)methoxy]benzene; 1-Bromo-4-(3-fluorobenzyloxy)benzene; (3-Fluorobenzyl) 4-bromophenyl ether; 4-Bromophenyl 3-fluorobenzyl ether; p-Bromophenyl 3-fluorobenzyl ether; [1,1'-Biphenyl]-4-ol, 3'-fluoro-4-bromo- (related structure); Benzene, 1-bromo-4-[(3-fluorophenyl)methoxy]-; CAS 1019123-14-8
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-[(3-Fluorophenyl)Methoxy]Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, GC, and NMR, are validated to provide reliable specifications for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.