Description

α,α-Dimethyl-4-(4-Methyl-1-Piperazinyl)Benzeneacetic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct piperazine-substituted aromatic structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas, offering a key building block for complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety in the research and development of new therapeutic molecules.
• Chemical Synthesis Research: Used in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	α,α-Dimethyl-4-(4-Methyl-1-Piperazinyl)Benzeneacetic Acid
CAS No.	1018660-87-1
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	2-(4-(4-Methylpiperazin-1-yl)phenyl)-2-methylpropanoic Acid; 4-(4-Methyl-1-piperazinyl)-α,α-dimethylbenzeneacetic Acid; α,α-Dimethyl-4-(4-methyl-1-piperazinyl)benzeneacetic Acid; 2-[4-(4-Methylpiperazin-1-yl)phenyl]-2-methylpropanoic Acid; 1018660-87-1; UNII-9H0F61B2MK; 9H0F61B2MK
EINECS	Contact for details

Quality Control

Our α,α-Dimethyl-4-(4-Methyl-1-Piperazinyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.