Description

1-Cbz-2-Cyanopiperidine is a high-purity, protected piperidine derivative widely utilized as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups, which enable selective chemical transformations, making it indispensable for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, particularly for applications in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those containing piperidine or piperazine scaffolds.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) and the construction of focused libraries for high-throughput screening.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid analog for designing peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or inhibitors for studying enzyme mechanisms and biological pathways.
• Agrochemical Development: Acts as a precursor in the research and synthesis of novel crop protection agents and pesticides.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and CRO laboratory settings.

Basic Information

Product Name	1-Cbz-2-Cyanopiperidine
CAS No.	1017788-63-4
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-cyanopiperidine; 2-Cyano-1-Cbz-piperidine; 1-Carbobenzoxy-2-cyanopiperidine; 1-(Benzyloxycarbonyl)-2-cyanopiperidine; 2-Cyano-N-Cbz-piperidine; Piperidine-2-carbonitrile, 1-[(phenylmethoxy)carbonyl]-; Benzyl 2-cyano-1-piperidinecarboxylate; 1-Cbz-piperidine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Cbz-2-Cyanopiperidine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.