Description

(2-Amino-6-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The protected amino group makes it valuable for constructing non-natural amino acid analogs and peptide-like molecules in drug discovery.
• Material Science: Employed in the synthesis of specialty polymers and advanced organic electronic materials where bromo and amino functionalities are required for further coupling reactions.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags, affinity probes, and other tools for biochemical research.

Basic Information

Product Name	(2-Amino-6-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1017781-88-2
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.16 g/mol
Synonyms	tert-Butyl (2-amino-6-bromophenyl)carbamate; N-Boc-2-Amino-6-bromoaniline; 2-Amino-6-bromo-N-Boc-aniline; 6-Bromo-2-[(tert-butoxycarbonyl)amino]aniline; 1-Bromo-3-[(tert-butoxycarbonyl)amino]-2-aminobenzene; 2-Bromo-6-[(tert-butoxycarbonyl)amino]aniline; Boc-2-Amino-6-bromoaniline; (2-Amino-6-bromophenyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (2-Amino-6-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.