Description

3-Ethoxy-2,4-Difluorobenzamide is a high-purity fluorinated benzamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern is critical for bioactivity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and amide functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoroethoxy moiety can enhance metabolic stability and binding affinity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs) due to its influence on molecular polarity and mesophase stability.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination and amidation reactions in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	3-Ethoxy-2,4-Difluorobenzamide
CAS No.	1017779-91-7
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	2,4-Difluoro-3-ethoxybenzamide; 3-Ethoxy-2,4-difluorobenzoic acid amide; Benzamide, 3-ethoxy-2,4-difluoro-; 2,4-Difluoro-3-ethoxybenzenecarboxamide; 3-Ethoxy-2,4-difluorobenzene-1-carboxamide; 1017779-91-7; AKOS025247065; SCHEMBL23538211
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,4-Difluorobenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.