Description

2-Ethoxy-3,5-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its difluoroethoxy-substituted phenylacetic acid structure enables precise molecular design. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Serves as a precursor for materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination chemistry and coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Ethoxy-3,5-Difluorophenylacetic Acid
CAS No.	1017779-85-9
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	2-(2-Ethoxy-3,5-difluorophenyl)acetic Acid; 3,5-Difluoro-2-ethoxyphenylacetic Acid; 2-Ethoxy-3,5-difluorobenzeneacetic Acid; (2-Ethoxy-3,5-difluorophenyl)acetic Acid; 1017779-85-9; Acetic acid, 2-(2-ethoxy-3,5-difluorophenyl)-; 2-Ethoxy-3,5-difluoro-α-toluic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-3,5-Difluorophenylacetic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.