Description

4-Ethoxy-2,3-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoroethoxy phenylacetic acid moiety can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electron-transport materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorination chemistry and the construction of complex aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Ethoxy-2,3-Difluorophenylacetic Acid
CAS No.	1017779-62-2
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	2-(4-Ethoxy-2,3-difluorophenyl)acetic acid; 4-Ethoxy-2,3-difluorobenzeneacetic acid; 2,3-Difluoro-4-ethoxyphenylacetic acid; (4-Ethoxy-2,3-difluorophenyl)acetic acid; α-(4-Ethoxy-2,3-difluorophenyl)acetic acid; 1017779-62-2; 4-Ethoxy-2,3-difluoro benzene acetic acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,3-Difluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.