Description

3-[5-Methyl-2-(Trifluoromethyl)Phenyl]Propionic Acid is a high-value fluorinated aromatic building block characterized by its propionic acid side chain and trifluoromethyl substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas targeting inflammation, central nervous system (CNS) disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for method development and exploring new fluorination chemistry and coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Item	Details
Product Name	3-[5-Methyl-2-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	1017779-28-0
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	3-[5-Methyl-2-(trifluoromethyl)phenyl]propanoic acid; 2-(Trifluoromethyl)-5-methylbenzenepropanoic acid; 3-(5-Methyl-2-(trifluoromethyl)phenyl)propanoic acid; α,α,α-Trifluoro-5-methyl-m-toluic acid, 3-carboxyethyl derivative; 3-(5-Methyl-2-(trifluoromethyl)phenyl)propionic acid; 1017779-28-0; 3-(5-Methyl-2-(trifluoromethyl)phenyl)propanoate
EINECS	Contact for details

Quality Control

Our 3-[5-Methyl-2-(Trifluoromethyl)Phenyl]Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acid nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.