Description

4-Ethoxy-3,5-Difluorobenzamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its value lies in its precise molecular architecture, featuring both ethoxy and difluoro substitutions on the benzamide core, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research: Utilized in academic and industrial labs for method development and exploring structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of complex, fluorinated molecules under cGMP or ISO standards.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorobenzamide
CAS No.	1017779-23-5
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	3,5-Difluoro-4-ethoxybenzamide; Benzamide, 3,5-difluoro-4-ethoxy-; 4-Ethoxy-3,5-difluorobenzoic acid amide; 1017779-23-5; AI3-63500; AKOS040759625; ZINC000068023647; SCHEMBL21824077
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP and ISO 9001 standards to meet the stringent requirements of pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.