Description

2,6-Difluoro-4-Ethoxyphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, central nervous system (CNS) disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms and ethoxy group contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce fluorinated phenylacetic acid moieties into polymer chains, enhancing material properties like chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new fluorination chemistry, cross-coupling reactions, and the development of novel chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2,6-Difluoro-4-Ethoxyphenylacetic Acid
CAS No.	1017779-16-6
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	2-(2,6-Difluoro-4-ethoxyphenyl)acetic Acid; 4-Ethoxy-2,6-difluorophenylacetic Acid; α-(2,6-Difluoro-4-ethoxyphenyl)acetic Acid; (2,6-Difluoro-4-ethoxyphenyl)acetic Acid; 1017779-16-6; DFEPA; Difluoroethoxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Ethoxyphenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) with complete batch-specific data are provided to guarantee traceability, consistency, and reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.