Description

4-Ethoxy-3,5-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine and ethoxy groups modulates biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenyl moiety enhances efficacy.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for optoelectronic devices.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel polymers and functional materials with specific properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorophenylacetic Acid
CAS No.	1017779-13-3
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	2-(4-Ethoxy-3,5-difluorophenyl)acetic Acid; 4-Ethoxy-3,5-difluorobenzeneacetic Acid; (4-Ethoxy-3,5-difluorophenyl)acetic Acid; 3,5-Difluoro-4-ethoxyphenylacetic Acid; 1017779-13-3; Acetic acid, 2-(4-ethoxy-3,5-difluorophenyl)-; 4-Ethoxy-3,5-difluorophenylaceticacid
EINECS	Contact for details

Quality Control

Every batch of 4-Ethoxy-3,5-Difluorophenylacetic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.