Description

2-Methoxy-6-(Trifluoromethyl)Phenylacetic Acid is a high-value, multi-functional aromatic acid building block characterized by its methoxy and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists, process scale-up teams, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of non-steroidal anti-inflammatory drugs (NSAIDs), kinase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral auxiliaries and specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.

Basic Information

Product Name	2-Methoxy-6-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1017779-10-0
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	2-Methoxy-6-(trifluoromethyl)benzeneacetic acid; [2-Methoxy-6-(trifluoromethyl)phenyl]acetic acid; α-(2-Methoxy-6-(trifluoromethyl)phenyl)acetic acid; 6-Trifluoromethyl-2-methoxyphenylacetic acid; o-Methoxy-α-(trifluoromethyl)phenylacetic acid; 2-(2-Methoxy-6-(trifluoromethyl)phenyl)acetic acid; (2-Methoxy-6-(trifluoromethyl)phenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.