Description

2-Fluoro-4,6-Bis(trifluoromethyl)benzamide is a high-value, fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring multiple fluorine atoms and an amide group, makes it a critical intermediate for developing novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials with unique dielectric properties.
• Fluorination Chemistry Studies: Employed as a model compound in academic and industrial research to study the effects of polyfluorination on aromatic systems and amide reactivity.
• Ligand and Catalyst Development: Utilized to synthesize novel ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.

Basic Information

Product Name	2-Fluoro-4,6-Bis(trifluoromethyl)benzamide
CAS No.	1017778-38-9
Molecular Formula	C9H4F7NO
Molecular Weight	275.13 g/mol
Synonyms	2-Fluoro-4,6-bis(trifluoromethyl)benzamide; 4,6-Bis(trifluoromethyl)-2-fluorobenzamide; Benzamide, 2-fluoro-4,6-bis(trifluoromethyl)-; 2-Fluoro-α,α,α,α',α',α'-hexafluoroisophthalamide; 1017778-38-9; AKOS040759625; Z57127455; FT-0773296
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4,6-Bis(trifluoromethyl)benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.