Description

2-Methyl-3-(Trifluoromethyl)Anisole is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the methoxy and trifluoromethyl substituents, which impart desirable electronic and steric properties to target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the construction of complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.

Basic Information

Product Name	2-Methyl-3-(Trifluoromethyl)Anisole
CAS No.	1017778-02-7
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	1-Methoxy-2-methyl-3-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-2-methylanisole; 2-Methyl-3-trifluoromethylanisole; 2-Methyl-α,α,α-trifluoro-m-anisole; m-Anisole, 2-methyl-3-(trifluoromethyl)-; Benzene, 1-methoxy-2-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Trifluoromethyl)Anisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC, HPLC, NMR, and FTIR to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.