Description

2-Chloro-6-Fluoro-3-Methoxyphenylacetonitrile is a versatile and high-value halogenated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables precise structural modifications. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the fluorine and chlorine atoms for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials due to its electron-withdrawing nitrile group and aromatic core.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methoxyphenylacetonitrile
CAS No.	1017777-64-8
Molecular Formula	C9H7ClFNO
Molecular Weight	199.61 g/mol
Synonyms	2-Chloro-6-fluoro-3-methoxybenzyl cyanide; (2-Chloro-6-fluoro-3-methoxyphenyl)acetonitrile; Benzeneacetonitrile, 2-chloro-6-fluoro-3-methoxy-; 2-Chloro-6-fluoro-3-methoxybenzenecetonitrile; α-Chloro-α-fluoro-3-methoxyphenylacetonitrile (isomer specific); CFMOPAN; CAS 1017777-64-8
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluoro-3-Methoxyphenylacetonitrile is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure batch-to-batch consistency and traceability. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.