Description

tert-Butyl (S)-Azepan-4-Ylcarbamate CAS NO 1017575-47-1 is a high-purity, chiral building block featuring a protected aminoazepane core. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries to construct complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Protease Inhibitor Synthesis: A key component in the construction of molecules designed to inhibit specific proteases, which are relevant in virology and oncology.
• Peptidomimetic Scaffold: The azepane ring system is used to create conformationally constrained peptide mimics for enhanced stability and bioavailability.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce chiral complexity into target molecules with high enantiomeric purity.

Basic Information

Product Name	tert-Butyl (S)-Azepan-4-Ylcarbamate
CAS No.	1017575-47-1
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(S)-4-((tert-Butoxycarbonyl)amino)azepane; (S)-tert-Butyl 4-aminoazepane-1-carboxylate; (S)-N-Boc-4-aminoazepane; (S)-1-Boc-4-aminoazepane; (S)-4-Aminoazepane-1-carboxylic acid tert-butyl ester; tert-Butyl (4S)-azepan-4-ylcarbamate; (S)-N-(tert-Butoxycarbonyl)-4-aminoazepane; Azepane-4-carboxamide, N-(1,1-dimethylethoxy)carbonyl-, (4S)-
EINECS	Contact for details

Quality Control

Our tert-Butyl (S)-Azepan-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.