Description

4'-Fluoro-3'-Methylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant synthetic utility. Its value lies in its role as a versatile intermediate for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the synthesis of fluorinated drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of fluorinated active pharmaceutical ingredients (APIs), leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluoromethylphenyl moiety is a critical structural component.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED device fabrication.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and specialty chemical industries.

Basic Information

Product Name	4'-Fluoro-3'-Methylpropiophenone
CAS No.	1017345-17-3
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	1-(4-Fluoro-3-methylphenyl)propan-1-one; 4-Fluoro-3-methylpropiophenone; 3-Methyl-4-fluoropropiophenone; 1-Propanone, 1-(4-fluoro-3-methylphenyl)-; 4'-Fluoro-3'-methylpropiophenone; 4-Fluoro-3-methyl-1-phenylpropan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3'-Methylpropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and stringent regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.