Description

3-Amino-4-Methyl-n-(2,2,2-Trifluoroethyl)Benzamide is a specialized trifluoroethyl-substituted benzamide derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the unique combination of an aromatic amine and a trifluoroethyl amide group, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine-tuning molecular structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoroethyl group can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers with specific thermal or chemical resistance properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on aromatic systems and amide bond characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific benzamide scaffold.

Basic Information

Item	Details
Product Name	3-Amino-4-Methyl-n-(2,2,2-Trifluoroethyl)Benzamide
CAS No.	1017019-26-9
Molecular Formula	C10H11F3N2O
Molecular Weight	232.20 g/mol
Synonyms	3-Amino-4-methyl-N-(2,2,2-trifluoroethyl)benzamide; N-(2,2,2-Trifluoroethyl)-3-amino-4-methylbenzamide; Benzamide, 3-amino-4-methyl-N-(2,2,2-trifluoroethyl)-; 3-Amino-4-methylbenzoic acid (2,2,2-trifluoroethyl)amide; 1017019-26-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Methyl-n-(2,2,2-Trifluoroethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.