Description

2-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]Acetonitrile is a high-value, heterocyclic organic building block featuring a fused pyridine-thiazole core with a reactive nitrile functional group. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for designing novel organic electronic materials, ligands for metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Employed as a building block for creating chemical probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry.
• Scale-up & Process Chemistry: Used in process optimization and kilogram-scale production for clinical trial material synthesis.

Basic Information

Product Name	2-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]Acetonitrile
CAS No.	1016888-78-0
Molecular Formula	C10H7N3S
Molecular Weight	201.25 g/mol
Synonyms	2-(4-(Pyridin-4-yl)-1,3-thiazol-2-yl)acetonitrile; 4-(2-Cyanomethyl)thiazol-4-ylpyridine; 2-[4-(4-Pyridinyl)-1,3-thiazol-2-yl]acetonitrile; (4-(Pyridin-4-yl)thiazol-2-yl)acetonitrile; Acetonitrile, 2-[4-(4-pyridinyl)-2-thiazolyl]-; Pyridine, 4-[2-(cyanomethyl)-4-thiazolyl]-; 1016888-78-0; 2-(4-Pyridin-4-yl-1,3-thiazol-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.