Description

2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Acetonitrile is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern synthetic chemistry. Its fused triazolopyridine core with an active acetonitrile side chain makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: A versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Bioconjugation: The reactive nitrile group can be utilized for linking molecules in probe and diagnostic reagent development.

Basic Information

Product Name	2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Acetonitrile
CAS No.	1016878-15-1
Molecular Formula	C8H6N4O
Molecular Weight	174.16 g/mol
Synonyms	2-(3-Oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-2-yl)acetonitrile; 2-(3-Oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-2-yl)acetonitrile; 2H,3H-[1,2,4]Triazolo[4,3-a]pyridin-3-one, 2-(cyanomethyl)-; 2-(Cyanomethyl)-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-3-one; [1,2,4]Triazolo[4,3-a]pyridin-3(2H)-one, 2-(cyanomethyl)-; CAS 1016878-15-1
EINECS	Contact for details

Quality Control

Our 2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.