Description

3-{[4-(Trifluoromethoxy)Benzyl]Thio}Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy and thioether functional groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated fluorinated molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group contributes to improved lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific surface properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms and protein interactions due to its reactive thioether moiety.

Basic Information

Product Name	3-{[4-(Trifluoromethoxy)Benzyl]Thio}Propanoic Acid
CAS No.	1016775-83-9
Molecular Formula	C11H11F3O3S
Molecular Weight	280.26 g/mol
Synonyms	3-[[[4-(Trifluoromethoxy)phenyl]methyl]thio]propanoic acid; 3-({[4-(Trifluoromethoxy)phenyl]methyl}sulfanyl)propanoic acid; 4-(Trifluoromethoxy)benzylthiopropionic Acid; α-Carboxyethyl 4-(Trifluoromethoxy)benzyl Sulfide; Propanoic acid, 3-[[[4-(trifluoromethoxy)phenyl]methyl]thio]-; 1016775-83-9
EINECS	Contact for details

Quality Control

Our production of 3-{[4-(Trifluoromethoxy)Benzyl]Thio}Propanoic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and compliance for pharmaceutical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.