Description

4-Chloro-2-Fluorobenzohydrazide is a high-purity fluorinated aromatic hydrazide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, enabling the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for improved bioactivity and environmental stability.
• Heterocyclic Chemistry: Serves as a versatile reagent for constructing pyrazole, triazole, and other nitrogen-containing heterocycles, which are core structures in many bioactive molecules.
• Material Science Research: Employed in the creation of specialty polymers and liquid crystals, where the chloro-fluoro substitution pattern can influence material properties.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	4-Chloro-2-Fluorobenzohydrazide
CAS No.	1016768-00-5
Molecular Formula	C7H6ClFN2O
Molecular Weight	188.59 g/mol
Synonyms	4-Chloro-2-fluorobenzoic acid hydrazide; 2-Fluoro-4-chlorobenzohydrazide; 4-Chloro-2-fluorobenzoylhydrazine; (4-Chloro-2-fluorophenyl)formohydrazide; Benzoic acid, 4-chloro-2-fluoro-, hydrazide; 1016768-00-5 (CAS); 4-Chloro-2-fluoro-benzoic acid hydrazide
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.