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2-Bromo-4-Fluoro-N,n-Dimethylbenzamide CAS NO 1016749-54-4
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CAS No.:1016749-54-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Bromo-4-Fluoro-N,n-Dimethylbenzamide is a high-purity, synthetically valuable aromatic amide derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
- Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated benzamide structures.
- Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization to create complex molecular libraries.
- Material Science: Intermediate in the production of specialty polymers and liquid crystals, where the bromo and fluoro substituents influence material properties.
- Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in drug discovery programs.
Basic Information
| Product Name | 2-Bromo-4-Fluoro-N,n-Dimethylbenzamide |
| CAS No. | 1016749-54-4 |
| Molecular Formula | C9H9BrFNO |
| Molecular Weight | 246.08 g/mol |
| Synonyms | N,N-Dimethyl-2-bromo-4-fluorobenzamide; 2-Bromo-4-fluoro-N,N-dimethylbenzamide; Benzamide, 2-bromo-4-fluoro-N,N-dimethyl-; 4-Fluoro-2-bromo-N,N-dimethylbenzamide; 1016749-54-4; AI3-63515; SCHEMBL2180557; ZINC000253899777; AKOS005259213; FT-0773296 |
| EINECS | Contact for details |
Quality Control
Our 2-Bromo-4-Fluoro-N,n-Dimethylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP and ISO 9001 standards where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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