Description

(2,5-Difluorophenyl)-(4-Piperidyl)Methanone is a high-purity organic building block featuring a piperidine core linked to a difluorinated aromatic ketone. This compound is valued for its role as a versatile intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and piperidyl motifs.
• Chemical Biology & Medicinal Chemistry: Serves as a core scaffold or precursor for designing and screening compound libraries in drug discovery programs.
• Ligand & Catalyst Development: Potential precursor for creating novel ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the synthesis of specialty polymers or advanced organic materials with specific electronic properties.

Basic Information

Product Name	(2,5-Difluorophenyl)-(4-Piperidyl)Methanone
CAS No.	1016743-93-3
Molecular Formula	C12H13F2NO
Molecular Weight	225.24 g/mol
Synonyms	4-(2,5-Difluorobenzoyl)piperidine; 1-(2,5-Difluorobenzoyl)piperidine-4-carboxaldehyde (precursor-related); 2,5-Difluorophenyl piperidin-4-yl methanone; 4-Piperidyl 2,5-difluorophenyl ketone; (2,5-Difluorophenyl)(4-piperidinyl)methanone; 1016743-93-3; 4-(2,5-Difluorobenzoyl)piperidine
EINECS	Contact for details

Quality Control

Our (2,5-Difluorophenyl)-(4-Piperidyl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.