Description

2-{4-[(2-Aminophenyl)Methoxy]Phenyl}Acetonitrile is a specialized aromatic nitrile derivative featuring both an amino and a methoxy functional group. This compound is a high-value pharmaceutical intermediate and organic synthesis building block, prized for its unique molecular scaffold that enables the construction of complex heterocyclic systems. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, or plant growth regulators that require a diphenyl ether-like structure.
• Material Science Research: Monomer or precursor for advanced polymers, liquid crystals, or organic electronic materials due to its rigid, conjugated backbone.
• Dye & Pigment Intermediate: Used in the synthesis of specialized azo dyes or functional pigments where the amino and nitrile groups facilitate chromophore development.
• Chemical Biology Probe Development: Serves as a scaffold for creating fluorescent tags or molecular probes for biological imaging and diagnostic applications.
• Catalyst Ligand Synthesis: The amino and ether functionalities can be modified to create novel ligands for transition metal catalysis in asymmetric synthesis.

Basic Information

Product Name	2-{4-[(2-Aminophenyl)Methoxy]Phenyl}Acetonitrile
CAS No.	1016525-01-1
Molecular Formula	C15H14N2O
Molecular Weight	238.29 g/mol
Synonyms	2-[4-[(2-Aminophenyl)methoxy]phenyl]acetonitrile; 2-(4-((2-Aminobenzyl)oxy)phenyl)acetonitrile; 4-[(2-Aminobenzyl)oxy]benzyl cyanide; (4-((2-Aminophenyl)methoxy)phenyl)acetonitrile; 2-Amino-α-(4-cyanomethylphenoxymethyl)benzene; 1016525-01-1; 2-(4-((2-Aminophenyl)methoxy)phenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our production of 2-{4-[(2-Aminophenyl)Methoxy]Phenyl}Acetonitrile adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity for critical R&D and scale-up processes. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and purification to meet specific project requirements, including chiral resolution if needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and may be hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent oxidation and moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.