Description

2-(Carbamoyloxymethyl)-1-Methyl-D3-5-Nitro-Imidazole is a high-purity, deuterated derivative of a key nitroimidazole scaffold, serving as a critical stable isotope-labeled intermediate. Its primary value lies in enabling advanced research and development in pharmaceutical chemistry, particularly for metabolic and pharmacokinetic (DMPK) studies. This compound is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require deuterium-labeled building blocks for the synthesis of novel drug candidates and analytical reference standards.

Application

• Pharmaceutical Intermediate: A key deuterated building block for the synthesis of novel, labeled drug candidates, particularly in antimicrobial and antiprotozoal research.
• Metabolic Studies (DMPK): Used in the preparation of internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) to improve the accuracy of drug metabolism and pharmacokinetic analyses.
• Isotope Labeling: Serves as a precursor for introducing stable deuterium (D) labels into target molecules to study reaction mechanisms and metabolic pathways.
• Analytical Reference Standard: Provides a certified material for use in quality control and method validation within analytical laboratories.
• Research Chemical: Employed in academic and industrial R&D for exploring structure-activity relationships (SAR) of nitroimidazole-based compounds.

Basic Information

Item	Details
Product Name	2-(Carbamoyloxymethyl)-1-Methyl-D3-5-Nitro-Imidazole
CAS No.	1015855-87-4
Molecular Formula	C7H7D3N4O4
Molecular Weight	217.18 g/mol
Synonyms	1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole-d3; 2-(Aminocarbonyloxymethyl)-1-methyl-5-nitro-1H-imidazole-d3; Deuterated Metronidazole Intermediate; 1-Methyl-5-nitro-2-[(aminocarbonyl)oxy]methyl-1H-imidazole-d3; D3-Labeled Nitroimidazole Carbamate; [1-Methyl-5-nitro-1H-imidazol-2-yl]methyl carbamate-d3; MNZ-d3 Intermediate; 5-Nitro-1H-imidazole-1-ethanol-d3, 2-(aminocarbonyloxy)methyl]-α-methyl-
EINECS	Contact for details

Quality Control

Our 2-(Carbamoyloxymethyl)-1-Methyl-D3-5-Nitro-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical and isotopic purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and deuterium enrichment is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.