Description

5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyridine class of heterocyclic compounds. This compound is valued for its unique molecular scaffold, which serves as a critical building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological pathways and enzyme functions.
• Agrochemical Research: Serves as a starting material for developing new active ingredients with potential herbicidal or pesticidal properties.
• Material Science: Investigated for its potential use in creating organic electronic materials due to its conjugated π-system.

Basic Information

Product Name	5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile
CAS No.	1015610-15-7
Molecular Formula	C8H4FN3
Molecular Weight	161.14 g/mol
Synonyms	4-Cyano-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-cyano-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 5-fluoro-; 5-Fluoro-4-(cyano)-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1015610-15-7)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.