Description

1,1,1-Trifluoro-n-[(11Br)-4-Oxido-2,6-Diphenyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]Methanesulfonamide is a sophisticated organophosphorus compound featuring a unique dinaphthodioxaphosphepin core structure. This high-value specialty chemical serves as a crucial chiral ligand or catalyst precursor in advanced synthetic organic chemistry, enabling highly selective transformations. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on developing novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or catalyst precursor in transition-metal catalyzed reactions such as hydrogenation, cross-coupling, and C-H activation for the synthesis of enantiomerically pure compounds.
• Pharmaceutical Intermediate Synthesis: A key building block or directing agent in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Advanced Material Research: Used in the development of novel organic electronic materials or polymers where its rigid, conjugated structure can impart specific electronic properties.
• Methodology Development: Serves as a test substrate or reagent in academic and industrial labs for developing new synthetic methodologies and catalytic cycles.
• Ligand Library Construction: A valuable component for creating diverse libraries of phosphine-based ligands for high-throughput screening in catalyst discovery.

Basic Information

Item	Details
Product Name	1,1,1-Trifluoro-n-[(11Br)-4-Oxido-2,6-Diphenyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]Methanesulfonamide
CAS No.	1010799-98-0
Molecular Formula	C33H19BrF3NO4PS
Molecular Weight	710.44 g/mol
Synonyms	(11bR)-4-Oxido-2,6-diphenyl-4-[[(trifluoromethyl)sulfonyl]amino]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; 1,1,1-Trifluoro-N-[(11bR)-4-oxido-2,6-diphenyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide; (R)-2,6-Diphenyl-4-(N-triflyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; Br-DPPON-Tf; Chiral Dioxaphosphepin Sulfonamide Ligand
EINECS	Contact for details

Quality Control

Every batch of our high-purity specialty chemicals is produced and verified under a strict quality management system. Standard analytical techniques including HPLC, NMR (1H, 13C, 31P), and mass spectrometry are employed to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. Handle and store under an inert atmosphere (argon or nitrogen) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.