Description

3-Oxo-3-(Tetrahydro-2H-Pyran-4-Yl)Propanenitrile is a versatile and high-purity chemical intermediate featuring a cyanoacetyl group attached to a tetrahydropyran ring. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitrile and ketone functionalities.
• Fine Chemical Building Block: Serves as a versatile synthon for constructing complex heterocyclic compounds and specialty chemicals used in material science.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for commercial-scale production.

Basic Information

Product Name	3-Oxo-3-(Tetrahydro-2H-Pyran-4-Yl)Propanenitrile
CAS No.	1010798-64-7
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	3-Oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile; 3-(Oxan-4-yl)-3-oxopropanenitrile; 4-(2-Cyanoacetyl)tetrahydropyran; 3-(Tetrahydro-2H-pyran-4-yl)-3-oxopropanenitrile; Propanenitrile, 3-oxo-3-(tetrahydro-2H-pyran-4-yl)-; 3-Oxo-3-(tetrahydropyran-4-yl)propanenitrile
EINECS	Contact for details

Quality Control

Our 3-Oxo-3-(Tetrahydro-2H-Pyran-4-Yl)Propanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.