Description

4-Fluoro-3-(Tetrazol-5-Yl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a boronic acid moiety with a tetrazole ring and a fluorine substituent, makes it an indispensable reagent for constructing complex molecules via cross-coupling reactions. This advanced intermediate is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in the development of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology, neurology, and metabolic disease research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioisosteric properties of the tetrazole ring.
• Material Science Research: Employed in the creation of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of activity-based probes and diagnostic agents.
• Academic & Contract Research: Essential for methodological development in organic synthesis and catalysis studies within university and CRO laboratories.

Basic Information

Product Name	4-Fluoro-3-(Tetrazol-5-Yl)Phenylboronic Acid
CAS No.	1009303-56-3
Molecular Formula	C7H6BFN4O2
Molecular Weight	207.95 g/mol
Synonyms	4-Fluoro-3-(1H-tetrazol-5-yl)benzeneboronic acid; (4-Fluoro-3-(1H-tetrazol-5-yl)phenyl)boronic acid; 3-(1H-Tetrazol-5-yl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-(tetrazol-5-yl)phenylboronic acid pinacol ester (common precursor); 5-(5-Borono-2-fluorophenyl)-1H-tetrazole; B-[4-Fluoro-3-(1H-tetrazol-5-yl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-(Tetrazol-5-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.