Description

1,1'-(1,3-Propanediyl)Bis[1,1-Bis(2-Methoxy-5-Methylphenyl)Phosphine] is a sophisticated, sterically hindered bisphosphine ligand, a critical component in advanced catalytic systems. Its value lies in enabling highly selective and efficient transition metal-catalyzed reactions, which are essential for producing complex molecules with high purity and yield. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for the development and scale-up of novel synthetic routes.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key chiral ligand for the enantioselective synthesis of pharmaceutical intermediates and active ingredients.
• Cross-Coupling Reactions: Facilitates critical C-C and C-X bond-forming reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, for constructing complex organic frameworks.
• Homogeneous Catalysis Research: Enables the development of new catalytic protocols in academic and industrial R&D laboratories.
• Fine Chemical Synthesis: Used in the production of high-value, structurally complex specialty chemicals and flavors/fragrances.
• Agrochemical Intermediate Production: Applied in the synthesis of advanced, high-performance active ingredients for crop protection.
• Material Science Precursor: Serves as a building block for novel organometallic complexes and functional materials.

Basic Information

Item	Details
Product Name	1,1'-(1,3-Propanediyl)Bis[1,1-Bis(2-Methoxy-5-Methylphenyl)Phosphine]
CAS No.	1009033-22-0
Molecular Formula	C39H44O4P2
Molecular Weight	638.71 g/mol
Synonyms	Bisphosphine Ligand (Propyl Bridge); 1,3-Propanediylbis[bis(2-methoxy-5-methylphenyl)phosphine]; DTBPM (Di-tert-butylphosphinomethane analog); Tris(o-anisyl)phosphine derivative; Chiral Diphosphine Ligand; Josiphos-type Ligand Analog; (R,R)- or (S,S)-1,1'-(1,3-Propanediyl)bis[1,1-bis(2-methoxy-5-methylphenyl)phosphine] (enantiomers); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of 1,1'-(1,3-Propanediyl)Bis[1,1-Bis(2-Methoxy-5-Methylphenyl)Phosphine] adheres to stringent quality protocols to ensure batch-to-batch consistency and performance in sensitive catalytic applications. All materials are characterized by NMR (¹H, ³¹P, ¹³C), HPLC, and elemental analysis to verify identity, purity, and chiral integrity where applicable. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert glovebox or under a positive pressure of inert gas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.