Description

tert-Butyl 2-[(4-Bromobenzoyl)Amino]Ethylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group and a brominated aromatic moiety. This compound is critical for medicinal chemists as it serves as a versatile building block for the synthesis of complex molecules, particularly in the development of protease inhibitors and other bioactive compounds. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors engaged in novel drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting enzymatic pathways.
• Protease Inhibitor Synthesis: Used as a core scaffold or side-chain component in the development of protease inhibitor drug candidates.
• Peptidomimetic Research: Employed in the design and construction of peptidomimetics due to its carbamate-protected aminoethyl backbone.
• Chemical Biology Probes: Utilized in the creation of labeled or tagged molecules for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up processes under cGMP or research-grade conditions.
• Library Synthesis for Drug Discovery: A valuable building block for generating diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	tert-Butyl 2-[(4-Bromobenzoyl)Amino]Ethylcarbamate
CAS No.	1008505-59-6
Molecular Formula	C14H19BrN2O3
Molecular Weight	343.22 g/mol
Synonyms	Boc-NH-CH2-CH2-NH-CO-(4-Br-Ph); 2-[(4-Bromobenzoyl)amino]ethyl carbamic acid tert-butyl ester; tert-Butyl N-[2-[(4-bromobenzoyl)amino]ethyl]carbamate; 4-Bromo-N-[2-[(tert-butoxycarbonyl)amino]ethyl]benzamide; (4-Bromobenzoyl)-β-alanine N-t-butylamide N-carbamate; BOC-EDA-4-Bromobenzamide; N-(tert-Butoxycarbonyl)-N'-(4-bromobenzoyl)ethylenediamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-[(4-Bromobenzoyl)Amino]Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.