Description

2-Methyl-5-Nitro-Pyridine-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, essential for modern cross-coupling reactions. Its core value lies in enabling the precise construction of complex heterocyclic scaffolds, a critical step in advanced chemical synthesis. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-couplings for synthesizing novel drug candidates, particularly those containing substituted pyridine cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, light-emitting diodes (OLEDs), and advanced polymers.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating fluorescent probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this precise boronic ester functionality.

Basic Information

Product Name	2-Methyl-5-Nitro-Pyridine-Boronic Acid Pinacol Ester
CAS No.	1008138-66-6
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	2-Methyl-5-nitropyridine-3-boronic acid pinacol ester; (2-Methyl-5-nitropyridin-3-yl)boronic acid pinacol ester; 5-Nitro-2-methylpyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-5-nitropyridine; 2-Methyl-5-nitro-3-pyridineboronic acid pinacol ester; Boronic acid, B-(2-methyl-5-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester; PINACOL 2-METHYL-5-NITROPYRIDINE-3-BORONATE
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Nitro-Pyridine-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.