Description

1-Pyrrolidinecarboxylic Acid, 2,2'-([1,1'-Biphenyl]-4,4'-Diyldi-1H-Imidazole-5,2-Diyl)Bis-, 1,1'-Bis(1,1-Dimethylethyl) Ester, (2S,2'S)- is a high-purity, chiral organic compound featuring a complex biphenyl-linked bis-imidazole structure with tert-butyl ester protecting groups. This compound is of significant value as a sophisticated building block or chiral ligand in advanced chemical synthesis, particularly for pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Catalyst/Ligand Development: Used in the research and development of asymmetric catalysts and chiral ligands for stereoselective synthesis.
• Agrochemical Research: Employed as a key intermediate in the development of new, high-efficacy crop protection agents and pesticides.
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic chemistry and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring high-complexity intermediates.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxylic Acid, 2,2'-([1,1'-Biphenyl]-4,4'-Diyldi-1H-Imidazole-5,2-Diyl)Bis-, 1,1'-Bis(1,1-Dimethylethyl) Ester, (2S,2'S)-
CAS No.	1007882-23-6
Molecular Formula	C38H46N6O4
Molecular Weight	650.82 g/mol
Synonyms	(2S,2'S)-1,1'-Di-tert-butyl 2,2'-(4,4'-biphenyldiylbis(1H-imidazole-5,2-diyl))dipyrrolidine-1-carboxylate; (2S,2'S)-Bis(1-(tert-butoxycarbonyl)-2-(4'-(1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidine; Chiral Biphenyl Bis-imidazole Derivative; tert-Butyl (S)-2-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, NMR, and MS for structural confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.