Description

1H-Isoindol-1-One, 7-Fluoro-2,3-Dihydro-6-Hydroxy- is a high-purity fluorinated isoindolinone derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with potential biological activity, particularly in the development of new therapeutic agents. This compound is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on drug discovery, process development, and the synthesis of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Organic Synthesis Reagent: Used as a versatile precursor for constructing complex heterocyclic compounds and fluorinated molecular architectures in medicinal chemistry.
• Research & Development: Essential for academic and industrial R&D programs investigating new chemical entities (NCEs) and structure-activity relationships (SAR).
• Fluorination Chemistry Studies: Serves as a model compound for studying the effects of fluorine substitution on molecular properties and reactivity.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.

Basic Information

Product Name	1H-Isoindol-1-One, 7-Fluoro-2,3-Dihydro-6-Hydroxy-
CAS No.	1007455-32-4
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	7-Fluoro-6-hydroxy-2,3-dihydro-1H-isoindol-1-one; 6-Hydroxy-7-fluoro-2,3-dihydro-1H-isoindol-1-one; 7-Fluoro-6-hydroxyisoindolin-1-one; 1H-Isoindol-1-one, 7-fluoro-2,3-dihydro-6-hydroxy-; 1007455-32-4; 7-Fluoro-6-hydroxy-2,3-dihydroisoindol-1-one
EINECS	Contact for details

Quality Control

Our 1H-Isoindol-1-One, 7-Fluoro-2,3-Dihydro-6-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.