Description

(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-(Phenylformamido)Hexanoic Acid is a sophisticated, high-purity amino acid derivative primarily used as a key building block in advanced peptide synthesis. This compound matters for its role in constructing complex peptide sequences with specific stereochemistry, enabling research and development in critical therapeutic areas. It is essential for pharmaceutical R&D scientists, peptide chemists, and manufacturers in the biotechnology sector who require reliable, high-quality intermediates for producing novel drug candidates and bioactive peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A critical Fmoc-protected amino acid derivative for the sequential assembly of custom peptides.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of peptide-based therapeutics and APIs.
• Bioconjugation & Probe Development: Used to introduce specific functional handles into peptides for labeling, imaging, or creating antibody-drug conjugates (ADCs).
• Chemical Biology Research: Enables the study of protein-protein interactions and cellular processes through the synthesis of tailored peptide probes.
• Process Development & Scale-Up: Supports the transition from laboratory-scale discovery to commercial manufacturing of peptide drugs.
• Custom Peptide Service Providers: A fundamental raw material for CROs and CDMOs offering bespoke peptide synthesis services.

Basic Information

Item	Details
Product Name	(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-(Phenylformamido)Hexanoic Acid
CAS No.	1007096-37-8
Molecular Formula	C28H26N2O5
Molecular Weight	470.52 g/mol
Synonyms	Fmoc-Lys(N-Phth)-OH; N6-Phthaloyl-Nα-Fmoc-L-lysine; Fmoc-Lys(Phth)-OH; N-α-Fmoc-N-ε-phthaloyl-L-lysine; Fmoc-Lys(Pht)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(1,3-dioxoisoindolin-2-yl)hexanoic acid; Fmoc-Lys(Nε-Phth)-OH; Nα-Fmoc-Nε-phthaloyl-L-lysine
EINECS	Contact for details

Quality Control

Our (2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-(Phenylformamido)Hexanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the stringent requirements of GMP environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.