Description

[6-(1-Ethyl-1H-Pyrazol-4-Yl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with a trifluoromethyl group. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, especially within oncology and central nervous system (CNS) research.

Application

This specialized chemical intermediate serves critical functions in sophisticated research and manufacturing processes.

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and pharmacokinetic profiles.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Potential application as an intermediate in the development of new generation pesticides and herbicides, leveraging its heterocyclic core.
• Material Science: Investigated for use in the synthesis of advanced organic electronic materials due to its conjugated system and fluorine content.

Basic Information

Product Name	[6-(1-Ethyl-1H-Pyrazol-4-Yl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1006444-20-7
Molecular Formula	C16H14F3N5O2
Molecular Weight	365.31 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-(1-ethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-; 6-(1-Ethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-ylacetic acid; (6-(1-Ethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; Acetic acid, [6-(1-ethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]-; CAS 1006444-20-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (NMR, IR, MS), and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.