Description

3-[5-Cyclopropyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Propanenitrile is a high-value, fluorinated pyrazole derivative serving as a critical synthetic intermediate in advanced chemical manufacturing. Its core value lies in the unique combination of the cyclopropyl and trifluoromethyl groups, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and environmental stability.
• Material Science Research: Used in the creation of specialty polymers and advanced organic materials that require specific fluorinated motifs for enhanced performance characteristics.
• Chemical Biology Probe Development: Utilized as a scaffold for creating tool compounds and probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-[5-Cyclopropyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Propanenitrile
CAS No.	1006334-01-5
Molecular Formula	C10H10F3N3
Molecular Weight	229.20 g/mol
Synonyms	3-(5-Cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanenitrile; 1H-Pyrazole-1-propanenitrile, 5-cyclopropyl-3-(trifluoromethyl)-; Propanenitrile, 3-[5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 5-Cyclopropyl-3-(trifluoromethyl)-1H-pyrazole-1-propanenitrile; 3-(5-Cyclopropyl-3-trifluoromethylpyrazol-1-yl)propionitrile
EINECS	Contact for details

Quality Control

Our production of 3-[5-Cyclopropyl-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Propanenitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.