Description

3-(4-Chloro-1H-Pyrazol-1-Yl)-2-Methylpropanenitrile CAS NO 1006328-60-4 is a high-value, functionalized pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity building block for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized pyrazole-based ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating functional polymers and organic electronic materials with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and inhibitors for biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-(4-Chloro-1H-Pyrazol-1-Yl)-2-Methylpropanenitrile
CAS No.	1006328-60-4
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Methyl-3-(4-chloro-1H-pyrazol-1-yl)propanenitrile; 3-(4-Chloro-1H-pyrazol-1-yl)-2-methylpropionitrile; 4-Chloro-1-(2-cyano-1-methylethyl)-1H-pyrazole; 1H-Pyrazole, 4-chloro-1-(2-cyano-1-methylethyl)-; 3-(4-Chloropyrazol-1-yl)-2-methylpropionitrile; 3-(4-Chloro-1-pyrazolyl)-2-methylpropionitrile; 1006328-60-4
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-1H-Pyrazol-1-Yl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.