Description

n-((R)-1-(Naphthalen-1-Yl)Ethyl)-3-(3-(Trifluoromethyl)Phenyl)Propanamide CAS NO 1005450-55-4 is a high-purity chiral organic compound featuring a naphthalene core linked to a trifluoromethylphenyl propanamide moiety. This molecule is of significant interest as a key chiral intermediate or building block in advanced synthetic chemistry, enabling the development of complex, optically active target molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for applications in drug discovery, agrochemical research, and the production of specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the specific stereochemistry influences biological activity.
• Ligand & Catalyst Development: Acts as a precursor or core structure for chiral ligands used in asymmetric catalysis.
• Material Science: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	n-((R)-1-(Naphthalen-1-Yl)Ethyl)-3-(3-(Trifluoromethyl)Phenyl)Propanamide
CAS No.	1005450-55-4
Molecular Formula	C22H20F3NO
Molecular Weight	371.40 g/mol
Synonyms	(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide; 1-Naphthaleneacetamide, N-[(1R)-1-(1-naphthalenyl)ethyl]-γ-oxo-3-(trifluoromethyl)-; (R)-1-(1-Naphthyl)ethyl-3-(3-trifluoromethylphenyl)propionamide; (R)-N-[1-(Naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propanamide; Propanamide, N-[(1R)-1-(1-naphthalenyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of n-((R)-1-(Naphthalen-1-Yl)Ethyl)-3-(3-(Trifluoromethyl)Phenyl)Propanamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and optical purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.