Description

Trifluoromethyl Dechloro CAS NO 1005193-64-5 is a specialized fluorinated organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in providing a reactive trifluoromethyl-containing building block, enabling the efficient introduction of fluorine atoms to enhance the properties of target molecules. This compound is essential for research and development chemists and process engineers working in the pharmaceutical, agrochemical, and advanced materials sectors, where fluorination is a key strategy for modulating bioactivity, stability, and physical characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing the trifluoromethyl group, which can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes due to their influence on electronic properties and stability.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, improving chemical resistance, reducing surface energy, and enhancing thermal stability.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and nucleophilic substitutions for constructing complex fluorinated architectures in medicinal and materials chemistry.
• Fluorinated Surfactant & Coating Precursor: Used to synthesize surface-active agents and specialty coatings that require oil- and water-repellent characteristics.

Basic Information

Product Name	Trifluoromethyl Dechloro
CAS No.	1005193-64-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Chloro-2,2,2-trifluoroethane; 2,2,2-Trifluoroethyl chloride; Trifluoroethyl chloride; 2-Chloro-1,1,1-trifluoroethane; α,α,α-Trifluoroethyl chloride; CF3CH2Cl; 1,1,1-Trifluoro-2-chloroethane; TFE-Cl
EINECS	Contact for details

Quality Control

Our Trifluoromethyl Dechloro is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its reactivity profile as a fluoride/strong alkali-sensitive compound, ensure storage containers are compatible and properly sealed to exclude moisture. Recommended storage temperature is 2-8°C for long-term stability, although short-term storage at controlled room temperature (15-25°C) may be acceptable. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density	Contact for details
Boiling Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.