Description

3-(1,1-Dioxo-Tetrahydrothiophen-3-Ylcarbamoyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex, functionalized bicyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used as a specialized building block for constructing unique molecular libraries in drug discovery and lead optimization programs.
• Protease Inhibitor Development: Its structural features make it a candidate for incorporation into molecules targeting specific enzyme families, such as proteases.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects requiring this precise chemical entity.

Basic Information

Product Name	3-(1,1-Dioxo-Tetrahydrothiophen-3-Ylcarbamoyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	1005068-61-0
Molecular Formula	C14H17NO5S
Molecular Weight	311.35 g/mol
Synonyms	5-Norbornene-2-carboxylic acid, 3-[[(1,1-dioxo-3-tetrahydrothienyl)carbonyl]amino]-; 3-[(1,1-Dioxotetrahydro-3-thienyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[(1,1-dioxo-3-tetrahydrothienyl)carbamoyl]-; 3-(1,1-Dioxotetrahydrothiophene-3-carboxamido)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(1,1-Dioxo-Tetrahydrothiophen-3-Ylcarbamoyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.