Description

(4-(Difluoromethoxy)-2-Fluorophenyl)Boronic Acid (Wxfc0673) is a high-purity, functionalized boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials. Its specific substitution pattern offers unique reactivity and selectivity for challenging synthetic targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and bioconjugates for diagnostic and research applications.
• Catalyst Ligand Development: Utilized to create sophisticated ligand systems for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(4-(Difluoromethoxy)-2-Fluorophenyl)Boronic Acid (Wxfc0673)
CAS No.	1004775-34-1
Molecular Formula	C7H6BF3O3
Molecular Weight	209.93 g/mol
Synonyms	[4-(Difluoromethoxy)-2-fluorophenyl]boronic acid; 2-Fluoro-4-(difluoromethoxy)benzeneboronic acid; (2-Fluoro-4-(difluoromethoxy)phenyl)boronic acid; Boronic acid, B-[4-(difluoromethoxy)-2-fluorophenyl]-; Wxfc0673; 4-(Difluoromethoxy)-2-fluorobenzeneboronic acid; B-(4-(Difluoromethoxy)-2-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of (4-(Difluoromethoxy)-2-Fluorophenyl)Boronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) in a desiccator to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.