Description

2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzonitrile is a high-value, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its molecular structure, featuring amino, chloro, and trifluoromethoxy substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and oncology, where the trifluoromethoxy group can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a vital building block for developing next-generation herbicides, fungicides, and insecticides, leveraging its unique halogenated structure for improved efficacy and environmental profile.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials due to its electron-withdrawing nitrile group and aromatic core.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating libraries of compounds for high-throughput screening.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments, where the amino and cyano groups facilitate chromophore development.

Basic Information

Product Name	2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzonitrile
CAS No.	1003708-19-7
Molecular Formula	C8H4ClF3N2O
Molecular Weight	236.58 g/mol
Synonyms	2-Amino-3-chloro-5-(trifluoromethoxy)benzonitrile; 3-Chloro-2-amino-5-(trifluoromethoxy)benzonitrile; Benzonitrile, 2-amino-3-chloro-5-(trifluoromethoxy)-; 2-Amino-3-chloro-α,α,α-trifluoro-p-anisonitrile; 2-Amino-3-chloro-5-(trifluoromethoxy)phenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.